I guess I forgot to mention that I got email back up first thing the next morning. It was a permissions problem … it happens everytime I upgrade vpopmail. It changes the user on the files to something other than it should be, so suddenly it can’t write to the folders/files. Once I remembered what happened last time it was an easy fix. I also had to update the config that allows me to run spamassassin and clamav on the emails. The upgrade dropped a new version of the integration script into production, but didn’t merge any of my config options. Oh well.